I've been getting ready to teach a class by trying to explain to myself the difference between truth and knowledge from a Lacanian perspective. I've been at it for a bit now, and I want to write down what I believe I've worked out.

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Knowledge:

Knowledge is comprised of things we can say. It is the stuff we can speak or explain to ourselves and others. I can share knowledge, and others can share knowledge with me.

Empirical pursuits like Science produce knowledge.

Truth:

The truth is outside of knowledge. It is what remains unsaid.

Even though we can't "speak the truth" (at least not all of it), it is good to try.